Outcomes in orthopedic device infections due to Streptococcus agalactiae: a retrospective cohort study

Outcomes in orthopedic device infections due to Streptococcus agalactiae: a retrospective cohort study

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Abstract Background Group B streptococci (Streptococcus agalactiae) (GBS) is a rare cause of prosthetic joint infection (PJI) occurring in patients with comorbidities and seems to be associated with a poor outcome.Depiction of GBS PJI is scarce in the literature.Methods A retrospective survey in 2 referral centers for bone joint infections was done Patients with a history of PJI associated with GBS between 2014 and 2019 were included.A descriptive analysis of treatment failure was done.

Risk factors of treatment failure were assessed.Results We included 61 patients.Among Floor Mops - Mops them, 41 had monomicrobial (67%) infections.The median duration of follow-up was 2 years (interquartile range 2.

35) Hypertension, obesity, and diabetes VITAMIN E 400IU mellitus were the most reported comorbidities (49%, 50%, and 36% respectively).Death was observed in 6 individuals (10%) during the initial management.The rate of success was 63% (26/41).Removal of the material was not associated with remission (p = 0.

5).We did not find a specific antibiotic regimen associated with a better outcome.Conclusion The results show that S.agalactiae PJIs are associated with high rates of comorbidities and a high treatment failure rate with no optimal treatment so far.